Surgical wound dehiscence develops when the edges of a surgical incision separate along the suture line due to infection or suboptimal healing, leading to an open wound. Surgical wound dehiscence can have a significant impact on the patient’s quality of life, increases the demands on healthcare professionals’ time and is costly to the health economy. Over 50% of patients with surgical wound dehiscence are managed in the community and treating these types of wounds is challenging. General practice nurses (GPNs) need to be aware of those patients that are more likely to present with surgical wound dehiscence and take a preventative approach, as well as understanding the principles of best practice for assessment and management when caring for this group of patients.