Endometriosis is a disease which presents with a number of signs and symptoms, often confusing clinicians who may easily mistake them for other conditions with similar symptoms. Diagnosis is therefore often confirmed a number of years after the initial onset of symptoms, resulting in reduced quality of life, particularly for those whose symptoms are severe. This article hopes to raise awareness among general practice nurses (GPNs) and non-medical prescribers, enabling them to suspect the condition and hopefully give women the opportunity to get their condition diagnosed at an earlier stage with subsequent earlier intervention and improved health and wellbeing in those affected by this unpleasant condition.